Tretinoin Gel (Tretinoin)
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Tretinoin Gel (Tretinoin)

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Tretinoin Gel (Retin-A Gel) is a reference medicine for treating acne and skin care with numerous therapeutic virtues. It ensures the appropriate skin care for both healthy skin and the skin with dermatological diseases.

Tretinoin was developed in the 1960s and is now essential in fighting against acne. This product is top-rated due to recognition of its new properties, such as enhancement of the regenerative processes in cells and skin rejuvenation.

Tretinoin Gel

Drug Info

  • Brand Name: Tretinoin Gel, Retin-A Gel, A-Ret Gel;
  • Active Ingredient: Tretinoin;
  • Manufacturer: Menarini.

Tretinoin Gel and its drug substance Tretinoin

This drug manages acne due to a special active ingredient, Tretinoin. The active substance has a unique mechanism of action and properties, including:

  • Tightens pores;
  • Accelerates the excretion of sebum accumulated in ducts;
  • Reduces inflammation in sebaceous glands;
  • Prevents the clogging;
  • Regulates skin oiliness;
  • Prevents the formation of new acne.

Among other key benefits of Tretinoin Gel is its ability to improve the appearance and texture of the skin:

  • The wrinkle reduction. Tretinoin smoothes fine lines and wrinkles. It increases the skin's density and elasticity, rejuvenating it.
  • Reduction of the visibility of spots and scars. The gel corrects acne scars, brightens sunspots, and evens out skin tone.
  • Skin renewal. Tretinoin Gel accelerates the renewal of epidermal cells, making the skin fresher and smoother, like new.

It should be mentioned that Tretinoin has excellent therapeutic effects. However, it may take several weeks before you see the result of regenerative processes.

Indications for use

Tretinoin Gel is licensed, approved, and certified for

  • Topical use in the treatment of acne.

Acne may be of any form and severity.

Treatment regimens and dosages

The standard way of using this drug is the following:

  • The usual dosage – a pea-sized amount of gel is applied once daily, usually in the evening;
  • The place of application – gel is applied to the T-zone, cheeks, or other areas with acne;
  • The duration of treatment – usually more than 7 weeks.

How to use Tretinoin gel

It is essential to prepare the skin before using the gel. Remove the makeup and clean your face with a mild skin cleanser. Wait a few minutes after cleaning the face until the skin is dry, then proceed to the next step.

Follow the recommendations given below:

  • Do not apply too much gel on your skin, and don’t use it more than once daily; it will not enhance its efficiency;
  • Distribute the gel evenly on the affected area of your skin and around it;
  • It is recommended to massage the skin while applying the gel;
  • Moisturize your skin when dryness or peeling appears; use sunscreen and nourishing masks;
  • Don’t worry if you experience an exacerbation of inflammation during the first weeks of therapy; this process is normal.

Using gel regularly following the manufacturer's recommendations is important to get the best results. Usually, the product is applied in the evening when you have no makeup on. Remember that improvement of the skin condition takes time, so be patient.

During Tretinoin Gel for acne use, you can put on makeup and apply your favorite moisturizers. Give preference to non-comedogenic products. If you have any doubts, consult a doctor or pharmacist to find the best option.

Missed Dose

Try to avoid dosing mistakes, like doubling or missing a dose. Nothing terrible will happen if you can’t or forget to apply the gel once. Just skip this dose and use another one as scheduled the next day.


You should consider the precautions listed below when using this product:

1. Avoid contact with sensitive areas.

Exclude Tretinoin Gel getting into the eyes, eyelids, nostrils, and mouth. In the event of accidental contact, rinse thoroughly with water to avoid irritation and discomfort.

2. Do not use several skin care products at once.

Please wait if you use other products. Your skin needs time to recover to avoid irritation.

3. Protect yourself from the sun and UV.

Sun exposure may lead to additional skin irritation. It is important to minimize sun exposure when using the gel. However, if you can’t avoid being in the sun, use sunscreen and a hat.

4. Take a pause after the sunburn treatment.

If you have a sunburn, wait till your skin fully recovers before starting or continuing acne treatment. If you spend the whole day in the sun, do not use this gel in the evening.

Use of Tretinoin Gel during pregnancy

Although Tretinoin Gel is usually applied on face skin and systemic absorption is minimal, it is not recommended to use it during pregnancy without consulting your doctor.

Possible side effects

The active ingredient Tretinoin acts on the skin surface or in the stratum corneum and is practically not absorbed into the bloodstream. Thus, most side effects are local and appear on the skin. The most common are the following:

1. Dryness

Dry skin is one of the most frequent adverse reactions when using Tretinoin Gel. It is related to the work of the active ingredient, which draws out excess sebum. The effect disappears after a few days as the skin gets used to the product.

2. Redness

Some people may notice redness in the areas of the gel application. Tretinoin stimulates blood circulation and cell renovation, so redness appears. However, this effect may indicate that you use too much gel.

3. Peeling

The side effect is associated with exfoliating the top layer of skin and stimulating cell renovation. It is recommended to use moisturizers to manage peeling.

4. Intensification of sensitivity to the sun

Renewed skin is more sensitive to UV light, so it’s important to use sunscreen and limit time spent in the sun before going outside.

5. Allergic reactions

Some people may experience allergic reactions to Tretinoin and other gel ingredients. It may manifest as itching, redness, rash, or edema. If you have the symptoms described above, stop using the product and consult with your doctor.

Tretinoin Gel for acne: interaction with other drugs

It is important to inform your doctor about all drugs you take:

  • Any creams and ointments, especially with high alcohol concentration;
  • Keratolytics (used to treat dry skin, calluses, etc.)

Skin irritation may appear or intensify under the influence of chlorinated or salt water, sunlight, or solarium.


You need to follow specific storage rules to preserve an acne drug's safety and efficacy until the expiration date. The recommended temperature is from 15° C to 30°C. Do not store in a bathroom or kitchen because these rooms are subjected to significant changes in humidity and temperature.

The best offer for Tretinoin Gel online on the market

We invest in innovations in the sphere of online marketing, work directly with manufacturers, and are ready to offer the best conditions for our clients:

1. Low prices

We deliver popular drugs and offer you to buy Tretinoin Gel at a reasonable price. Our offers and discounts make medication purchases more affordable.

2. Timely delivery

We value our clients' time and do everything possible to make delivery convenient and easy.

3. Convenient and fast order process

At our online pharmacy, you can easily and quickly order Tretinoin Gel without a prescription with your smartphone or laptop. Placing an order will take a few minutes and be stress-free and convenient.

4. The high level of service

We value our reputation and do everything possible so our clients feel satisfied. We offer the best service so you become our loyal customers.

5. 24/7 availability

Our online pharmacy is available 24/7, so you can contact our managers anytime. Competent specialists are always ready to provide quality advice and assistance in choosing products.

How to buy Tretinoin gel online

Placing an order is quick and easy. Choose the necessary product, dosage, and quantity, and click the "Buy" button. In our online pharmacy, the drug is available in different dosages:

  • A-Ret Gel 20g 0.025 %
  • A-Ret Gel 20g 0.05 %
  • A-Ret Gel 20g 0.1 %

Click the cart icon in the upper right corner of the screen to view the goods in the shopping cart or complete your order.

The next step is to fill in the required fields (full name, phone number, shipping address, email, etc.), choose a payment method, and pay for the order. We ship products from the nearest warehouse to make delivery faster.

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